Serum Amyloid A Semi-QuantitativeRapid Test Device (Whole Blood/Serum/Plasma)
SUMMARY
The Serum amyloid A (SAA) is normally found complexed with lipoproteins and
different isoforms have been described with numbers varying by species.47 SAA
represents one of the most conserved proteins among mammals supporting the
premise that it has a basic and essential role in the innate immune system. In
species with CRP, SAA often mirrors the magnitude and time course of the
response.48 Studies have demonstrated SAA activity in chemotaxis of leukocytes as
well as the induction of additional proinflammatory cytokines.49,50 In addition,
SAA has also been described to induce extracellular matrix degrading enzymes
which can assist in tissue repair.47
The Serum amyloid A Semi-Quantitative Rapid Test Cassette (Whole
Blood/Serum/Plasma) is a rapid test that semi-qualitatively detects the presence of
Serum amyloid A in whole blood, plasma or serum specimens at the sensitivity of
10ng/mL, 30ng/mL and 60ng/mL. The test utilizes a combination of monoclonal
antibodies to selectively detect elevated levels of Serum amyloid A in whole blood,
plasma or serum. At the level of claimed sensitivity, the Serum amyloid A
Semi-Quantitative Rapid Test Cassette (Whole Blood/Serum/Plasma) shows no
cross-reactivity interference from the structurally related CRP, PCT or others at
high physiological levels.
INTERPRETATION OF RESULTS
The COVID-19 IgG/IgM Rapid Test Device (Whole Blood/Serum/Plasma) is a qualitative membrane-based immunoassay for the detection of COVID-19 antibodies in whole blood, serum, or plasma. This test consists of two components, an IgG component and an IgM component. In the Test region, anti-human IgM and IgG is coated. During testing, the specimen reacts with COVID-19 antigen-coated particles inthe test strip. The mixture then migrates upward on the membrane chromatographically by capillary action and reacts with the antihuman IgM or IgG in test line region. If the specimen contains IgM or IgG antibodies to COVID-19, a colored line will appear in test line region.Therefore, if the specimen contains COVID-19 IgM antibodies, a colored line will appear in test line region M. If the specimen contains COVID-19 IgG antibodies, a colored line will appear in test line regionG. If the specimen does not contain COVID-19 antibodies, no colored line will appear in either of the test line regions, indicating a negative result. To serve as a procedural control, a colored line will always appeared in the control line region, indicating that the proper volume of specimen has been added and membrane wicking has occurred.
WARNINGS AND PRECAUTIONS
NOTE
1. The intensity of the color in the test region (T) may vary depending on the concentration of
analytes present in the specimen. Therefore, any shade of color in the test region should be
considered positive. Please note that this is a semi‐quantitative test only, and cannot determine
the concentration of analytes in the specimen.
2. Insufficient specimen volume, incorrect operating procedure or expired tests are the most
likely reasons for control band failure.
