Products

During blood coagulation process, fibrinogen is converted to fibrin by the activation of thrombin. The resulting fibrin monomers polymerise to form a soluble gel of non‐cross‐linked fibrin. This fibrin gel is then converted to cross‐linked fibrin by thrombin activated Factor XIII to form an insoluble fibrin clot. Production of plasmin, the major clot‐lysing enzyme, is triggered when a fibrin clot is formed. Although fibrinogen and fibrin are both cleaved by the fibrinolytic enzyme plasmin to yield degradation products, only degradation products from cross‐linked fibrin contain D‐dimer and are called cross‐linked fibrin degradation products. Therefore, fibrin derivatives in human blood or plasma containing D‐dimer are a specific marker of fibrinolysis. The D‐dimer Rapid Test Device (Whole Blood/Plasma) is a rapid test that qualitative detects the presence of D‐dimer in whole blood or plasma specimens at the sensitivity of 500ng/mL. The test utilizes a combination of monoclonal antibodies to selectively detect elevated levels of D‐dimer in whole blood or plasma. At the level of claimed sensitivity, the D‐dimer Rapid Test Cassette (Whole Blood/Plasma) shows no cross‐reactivity interference from the related Troponin I, Troponin T, CK‐MB, Myoglobin or others at high physiological levels